SERVICES
Therapeutic
Plasma Exchange
(TPE) by Circulate
Advanced Biological Optimization
At Docere Clinics, we are dedicated to providing the most advanced therapies to support systemic health and longevity in a safe and responsible manner.
We are thrilled to offer Therapeutic Plasma Exchange (TPE), powered by Circulate, a procedure designed to filter key circulating factors related to aging and inflammation.
Advanced Biological Optimization
At Docere Clinics, we are dedicated to providing the most advanced therapies to support systemic health and longevity in a safe and responsible manner.
We are thrilled to offer Therapeutic Plasma Exchange (TPE), powered by Circulate, a procedure designed to filter key circulating factors related to aging and inflammation.
What is TPE?
The Science of Plasma Filtration
Therapeutic Plasma Exchange (TPE) is an established medical treatment that filters the blood to remove inflammatory, disease-causing, and age-accelerating substances.
During the procedure:
- Blood is drawn and passed through an apheresis device that separates and removes the plasma.
- The plasma, where these substances are concentrated, is discarded.
- The removed plasma is then replaced with an
albumin solution (a protein), and the cleansed blood is returned to the patient.
TPE is used to manage a variety of autoimmune, metabolic, and age-related conditions.
Evidence-Based Results: The Circulate Trial
Our program is grounded in the findings of the Circulate Trial (published July 2024), which studied the effects of TPE, particularly when combined with
Intravenous Immunoglobulin (IVIG).
Key Findings from the Trial
- Reduced Biological Age: Participants who received TPE with IVIG experienced an average reduction of 2.6 years in biological age after six sessions over three months.
- Immune System Support: The TPE-IVIG combination reversed age-related immune decline, increasing protective immune cells (CD8 and CD4 naïve T cells).
- Improved Biomarkers: TPE led to significant changes at the molecular level, improving proteins, lipids, and inflammatory markers associated with aging.
- Broad Benefits: The treatment benefited healthy individuals, who experienced enhanced balance and strength, and those with higher risk factors, who saw the greatest reduction in biological age.
Who is a Candidate?
TPE is a targeted therapy that supports individuals focused on optimizing their health and managing chronic conditions. Individuals who typically benefit include:
- Those focused on longevity and anti-aging health goals.
- Patients dealing with chronic inflammatory conditions.
- High-performance individuals and athletes.
- Individuals seeking to support their system following post-viral or immune-compromised states.
- Protocol Note:
We may discuss the addition of IVIG to your treatment, as it is proven to replenish beneficial antibodies and enhance immune support as well as birth tissue derived extracellular vesicles by Vitti Labs. A consultation with our medical providers is required to determine if TPE is a suitable part of your comprehensive health plan.
Is TPE Right For You?
A consultation by our clinical staff is required before scheduling a procedure to determine if you are a candidate. Click below to see if we are right for you.